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US Health Secretary Robert F Kennedy Jr said Thursday that firing a top government scientist was "absolutely necessary" as he faced blistering criticism from Democrats urging him to resign over his steps to curb vaccines.The Senate hearing, marked by sharp exchanges that often erupted into shouting matches, came days after the ouster of Sue Monarez, the former director of the Centres for Disease Control and Prevention (CDC).Her dismissal, accompanied by several high-level resignations and hundreds of earlier layoffs, has plunged the nation's premier public health agency into turmoil.In his opening remarks, Kennedy tore into the CDC's actions during the coronavirus (Covid-19) pandemic, accusing the agency of failing "miserably" with "disastrous and nonsensical" policies including masking guidance, social distancing and school closures.Kennedy said that the CDC, during the pandemic, had lied to Americans, pointing to recommendations on mask wearing, vaccine boosters and social distancing and statements that the vaccine would prevent transmission."I need to fire some of those people and make sure this doesn't happen again," he said."We need bold, competent and creative new leadership at CDC, people able and willing to chart a new course," he said, touting the health department's new focus on chronic disease and promoting prevention.Monarez, the CDC director whom Kennedy previously endorsed, accused the secretary of a "deliberate effort to weaken America's public-health system and vaccine protections" in a *Wall Street Journal op-ed Thursday.Kennedy's explanation for her firing – as he told Senator Elizabeth Warren – was simply: "I asked her, 'Are you a trustworthy person?' And she said, 'No.'"Once a respected environmental lawyer, Kennedy emerged in the mid-2000s as a leading anti-vaccine activist, spending two decades spreading voluminous misinformation before being tapped by President Donald Trump as health secretary in his second administration.Since taking office, he has restricted Covid-19 shots to narrower groups, cut off federal research grants for the mRNA technology credited with saving millions of lives, and redirected funding toward research on debunked claims linking vaccines to autism.Ron Wyden, the top Democrat on the Senate Finance Committee leading the hearing, set the tone by demanding Kennedy be sworn in under oath – accusing him of lying in prior written testimony when he pledged not to limit vaccine access."It is in the country's best interest that Robert Kennedy step down, and if he doesn't, Donald Trump should fire him before more people are hurt," Wyden thundered.However, Republican committee chairman Mike Crapo shot down the request, praising Kennedy's focus on chronic diseases such as obesity.The exchanges only grew more ill-tempered.Democratic Senator Maria Cantwell branded Kennedy a "charlatan" over his attacks on mRNA research, while Kennedy accused Senator Maggie Hassan of "crazy talk" and "making things up to scare people" when she said that parents were already struggling to get Covid-19 vaccines for their children.Vaccines have become the flashpoint in an ever-deepening partisan battle.Conservative-leaning Florida on Wednesday announced that it would end all immunisation requirements, including at schools, while a West Coast alliance of California, Washington and Oregon announced they would make their own vaccine recommendation body to counter Kennedy's influence at the national level.Republicans mostly closed ranks around Kennedy, though there was some notable dissent.Senator Bill Cassidy, a physician whose support was key to Kennedy's confirmation, criticised his cancellation of mRNA grants.He was joined by fellow Republican doctor Senator John Barrasso and Senator Thom Tillis.Cassidy pressed Kennedy on whether Trump deserved a Nobel Prize for Operation Warp Speed, the public-private partnership that sped Covid-19 vaccines to market.Kennedy agreed that Trump should have received the prize but in nearly the same breath, praised hydroxychloroquine and ivermectin, drugs championed by conspiracy theorists that have been proven ineffective against Covid-19.

US Senator Bernie Sanders has called on Secretary of Health and Human Services Robert F Kennedy Jr to resign, days after a senior public health official was fired and four others resigned in disputes over Kennedy's unorthodox opposition to vaccines.Sanders, an independent senator from Vermont who caucuses with Democrats, wrote in a *New York Times guest essay that Kennedy is "endangering the health of the American people now and into the future”.This week, Kennedy ousted the director of the Centres for Disease Control and Prevention (CDC), Susan Monarez, less than a month into her tenure, deepening disarray at the nation's main public health agency.Monarez had refused to adopt new limitations on the availability of some vaccines urged by Kennedy, saying they went against scientific evidence.Four other senior CDC officials resigned in protest, citing anti-vaccine policies and misinformation promoted by Kennedy and his team; hundreds of their colleagues walked out of the CDC's headquarters in Atlanta in support of the departing leaders.Sanders, the ranking member of the Senate's health committee and an opponent of Kennedy's confirmation earlier this year, wrote that Kennedy ousted Monarez because she refused "to act as a rubber stamp for his dangerous policies”."Despite the overwhelming opposition of the medical community, Secretary Kennedy has continued his longstanding crusade against vaccines and his advocacy of conspiracy theories that have been rejected repeatedly by scientific experts," Sanders wrote.He said that vaccines for diseases such as polio and coronavirus (Covid-19) had saved hundreds of millions of lives around the world.A spokesperson for Kennedy did not respond to a request for comment.Kennedy, a lawyer and prominent anti-vaccine advocate, ran an unsuccessful campaign for the presidency last year.He espouses healthy eating, natural foods and exercise, but also frequently shares his theories about vaccines and other medical issues that many doctors and scientists say are groundless and drawn from the conspiratorial fringe.On Wednesday, Kennedy baffled doctors when he said he kept seeing children walking through airports that he had diagnosed as "overburdened with mitochondrial challenges, with inflammation", based on their faces and body movements.President Donald Trump, a Republican, nominated Kennedy to become the health secretary earlier this year and he was sworn in in February.Kennedy emphasised in a congressional hearing in May that he did not think Americans should ever take medical advice from him.