Weather inshore until 6:00 pm on Monday will be hot daytime with a chance of local clouds by noon, the Department of Meteorology said in its daily weather report.Offshore, the weather will be fine, the report added.Wind inshore will be variable mainly southwesterly to southeasterly at a speed of 3 - 13 KT, becomes northwesterly to northeasterly at a speed of 5 - 15 KT.Offshore, it will be variable southwesterly to northwesterly at a speed of 3 - 13 KT, becomes southeasterly to northeasterly.Sea state inshore will be 1 - 2 ft; while offshore, it will be 1 - 3 ft.Visibility inshore and offshore will be 5 - 10 km.Area High Tide Low Tide Max-------------------------------------------------------------------Doha 02:09 - 15:24 08:27 - 23:10 40Mesaieed 03:45 - 17:04 00:42 - 09:18 38Wakrah 01:51 - 16:19 09:02 - 23:11 38Al Khor 15:42 - 03:51 23:21 - 09:51 41Ruwais 03:51 - 15:42 09:51 - 22:39 39Dukhan 08:30 - 20:44 02:21 - 14:27 40Abu Samra 07:47 - 20:13 03:06 - 12:46 39Sunrise: 05:20 LTSunset: 17:36 LT

Qatar University (QU) scientists have made a major breakthrough in the field of precision medicine, offering new hope for the treatment of chronic diseases. In a recent study published in Pharmacology and Translational Science by the American Chemical Society, researchers from QU Health revealed the potential of Apabetalone (RVX-208).The innovative epigenetic therapy, which targets the way genes are turned on or off in human bodies without changing the DNA sequence, is poised to transform the treatment of cardiovascular, renal, neurological, viral, and cancer disorders by addressing their underlying causes.Epigenetic treatments like Apabetalone block specific harmful proteins, reducing their production. Apabetalone is the only such inhibitor that has been granted a breakthrough therapy designation from the US Food and Drug Administration (FDA) outside the area of oncology.Dr Zaid al-Ma'ayah, assistant professor Pharmacology and Toxicology at QU, leading the study, said: “This work represents a new era in medicine, focusing on using epigenetics to regulate the transcription of genes involved in cardiovascular, infectious, and cancer disorders. In addition to this work, we have made numerous intriguing experimental discoveries regarding the new applications of this epigenetic therapy, which we will soon share with the scientific community. We are sincerely thankful to the College of Pharmacy and QU Health Sector for their support of our work.”Unlike traditional treatments that target just one part of a disease, Apabetalone takes a revolutionary approach by working earlier in the process and affecting many biological functions. It blocks proteins that play a role in disease development, creating a new way to treat chronic illnesses. This method improves how cells communicate locally and throughout the body, leading to better overall health and wellness. This marks a major advancement in medical science.Because of the high impact of changes in how genes work, especially when certain proteins are modified, the researchers wanted to see how Apabetalone could help in early tests with animals. They plan to look into using Apabetalone with other treatments to make it even better at protecting health. As Apabetalone moves through clinical trials (tests in people), continued preclinical research is essential to fully understand its potential across various diseases.This cutting-edge study was enriched by the dedicated efforts of Hevna Dhulkifle, a QU Health graduate student, whose contributions were integral to the study’s findings. Dhulkifle remarked: “The state-of-the-art research facilities and the fostering environment in QU have greatly enriched my academic journey. The recent review is a testament to the university's commitment to stay at the forefront of scientific advancements. I am truly grateful to learn from and work with some of the brightest minds in the field.”The study, funded by an internal grant from QU, highlights the university’s commitment to staying at the forefront of scientific research. The support of the university has allowed researchers to explore new frontiers in epigenetic therapies, offering hope for the future of precision medicine.

Highlighting the strides Qatar is making in technology in the construction and services sectors, the ConteQ Expo24 started Monday at the Qatar National Convention Centre. Held under the patronage of HE the Prime Minister and Minister of Foreign Affairs Sheikh Mohamed bin Abdulrahman bin Jassim al-Thani, the three day expo is an important milestone in promoting innovation, digitisation and sustainable development in the two sectors.HE the Minister of Municipality Abdullah bin Hamad bin Abdullah al-Attiyah delivered the opening address in the presence of HE the Minister of Transport Jassim bin Saif al-Sulaiti, HE Minister of Communications and Information Technology Mohammed bin Ali al-Mannai, president of Ashghal Dr Engineer Saad bin Ahmad al-Muhannadi, ambassadors and dignitaries from various government and private entities.HE the Municipality Minister said Qatar is moving towards a comprehensive digital transformation through numerous initiatives and investments in technology, innovation, and artificial intelligence, with the aim of achieving comprehensive economic development, a key pillar of the Qatar National Vision 2030, striving to build a more productive, diversified and competitive national economy while maintaining the highest quality standards and sustainability.HE the Minister added that digital transformation is a strategic axis for supporting global Sustainable Development Goals by enhancing innovation, achieving resource efficiency, and improving the quality of life in various communities.“ConteQ Expo 2024 is the first of its kind in Qatar, attracting major global entities and marking the beginning of a new era of innovation initiatives in construction technology, the services sector, and digital transformation, adding that it aims to enhance partnerships in these important sectors, explore promising investment opportunities and attract them to Qatar,” HE the Minister noted adding that Qatar's hosting of this important event will contribute significantly to achieving the desired digital transformation in the construction sector, harnessing the latest construction technology and services to improve performance efficiency, reduce human errors, unskilled labour, save energy, and achieve environmentally sustainable development.HE the Municipality Minister exuded his confidence that this exhibition will be a cornerstone and the beginning of a fruitful journey of new partnerships and investments that will enhance the country's economy and benefit all participating entities. Al-Attiyah underlined that Qatar has substantial investments in digital infrastructure and business incubator programs and called on investors and international companies to take advantage of the country’s investment opportunities.The exhibition is a collaborative effort between four governmental entities namely the Ministry of Commerce & Industry (MOCI), the Ministry of Communications and Information Technology (MCIT), the Ministry of Labour (MOL), and the Public Works Authority 'Ashghal', with NeXTfairs for conferences & Exhibitions as the organiser. It features more than 60 speakers and 250 exhibitors and partners.