Israel and Hamas resumed ceasefire talks on Saturday in Qatar, both sides said, even as Israeli forces ramped up a bombing campaign that has killed hundreds of people over 72 hours, and mobilised for a massive new ground assault.

Palestinian health authorities said at least 146 people had been confirmed killed in the third day of Israel's latest bombing campaign, one of the deadliest waves of strikes since a ceasefire collapsed in March. Many hundreds more wounded were being treated in hospital, and countless others were still buried under rubble.

Israel says it is mobilising to seize more ground in Gaza in a new campaign dubbed "Operation Gideon's Chariots", which follows a visit this week to the Middle East by US President Donald Trump. It has halted all supplies entering Gaza since the start of March, leading to rising international concern over the plight of the enclave's 2.3 million residents.

Taher Al-Nono, the media advisor for the Hamas leadership, told Reuters a new round of indirect talks with the Israeli delegation in Doha began on Saturday, discussing all issues "without pre-conditions".

"The Hamas delegation outlined the position of the group and the necessity to end the war, swap prisoners, the Israeli withdrawal from Gaza, and allowing humanitarian aid and all the needs of the people of Gaza back into the strip," he added.

Israeli Defence Minister Israel Katz also said in a statement that negotiations on a deal to release Israeli hostages held by Hamas had resumed in Doha. He noted that the talks had started without Israel first agreeing to a ceasefire or to lift its blockade.

Israel's military said it was conducting extensive strikes and mobilising troops with the aim of achieving "operational control" in parts of Gaza.

Gaza health authorities said most of those killed on Saturday were in towns on the northern edge of the enclave, including Beit Lahiya and the Jabalia refugee camp, as well as in the southern city of Khan Younis. They said 459 people had been injured.

Israeli forces had told people to leave the northern areas on Friday.

"Northern Gaza is witnessing a systematic campaign of extermination," Hamas said in a statement, calling on Arab leaders at a summit in Baghdad to take practical steps to stop the aggression and ensure the delivery of aid.

At the Arab League summit, Egypt's President Abdel-Fatah al-Sisi, whose country mediates Gaza peace talks alongside Qatar, said Israel's actions aimed at "obliterating and annihilating" the Palestinians and "ending their existence in the Gaza Strip".

United Nations experts say famine now looms in Gaza more than two months after Israel halted all deliveries of supplies. UN aid chief Tom Fletcher asked the Security Council this week if it would act to "prevent genocide".

On Friday, Trump acknowledged Gaza's growing hunger crisis and the need for aid deliveries.

A US-backed foundation aims to start distributing aid to Gazans by the end of May using private US security and logistics firms. The UN has said it won't work with the group because it is not impartial, neutral or independent.

Gaza's health system is barely operational with hospitals hit repeatedly by the Israeli military during the 19-month war and medical supplies drying up.

The head of the Indonesian Hospital in northern Gaza, Marwan Al-Sultan, said huge numbers of wounded victims of the latest bombing campaign were in critical condition.

"Since midnight, we have received 58 martyrs, while a large number of victims remain under the rubble. The situation inside the hospital is catastrophic," he said on X.

NBC News reported on Friday, citing five people with knowledge of the matter, that the Trump administration is working on a plan to permanently relocate as many as one million Palestinians from the Gaza Strip to Libya. All major Palestinian political groups reject any such displacement.