A suicide attacker blew himself up outside a Sufi shrine in southwest Pakistan on Thursday, killing 18 people and wounding at least 27 others, officials said, as people attended annual celebrations of a local saint.
The incident follows a deadly bomb attack on the same shrine in the oil and gas rich Balochistan province in 2005, which killed 35 people.
"A suicide bomber blew himself up after he was intercepted by police guards on duty outside the shrine, killing 18 people including three children under the age of 12 and two policemen, and wounding at least 27 others, 14 of them seriously," provincial home secretary Akbar Harifal told AFP.
People make daily visits to the shrine in Jhal Magsi district, with attendance climbing significantly during festivities.
Harifal said the seriously injured patients were being airlifted to southern Sindh province in the absence of adequate medical facilities in restive Balochistan. 
The explosion triggered panic, with worshippers shouting and running in different directions, officials at the site told AFP. 
Provincial home minister Sarfaraz Bugti also confirmed the toll.
"The suicide bomber struck outside the shrine at a time when it was packed with people attending anniversary celebrations of Syed Cheesal Shah," said senior local administration official Asad Kakar, referring to a local saint.
Balochistan government spokesman Anwaar-ul-Haq Kakar said there were confirmed reports of a suicide attack.
There was no immediate claim of responsibility but militants and separatists have repeatedly targeted minority people at religious sites, as well as security officials.
Balochistan is afflicted by militancy, sectarian violence and a separatist insurgency.
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