Al-Sada said Qatar wanted to build on Doha's good ties with Washington and shrugged off fears about any protectionist policies under US President Donald Trump.
"We have an excellent relationship with the US on all fronts," al-Sada said on the fringes of a Qatari government-organised press trip in Doha.
He said US energy giants ExxonMobil, ConocoPhillips and Chevron Phillips were already working in Qatar.
"We built an excellent relationship and we invested in the US and we are looking for opportunities to invest in the US," he said.
Asked about the potential impact of Trump's presidency on international trade, al-Sada said he would adopt a wait-and-see approach.
"But we are sure that any policy coming up from the US will be supportive to their own country as well as the rest," said the minister.
Qatar is the world's biggest producer and exporter of liquefied natural gas (LNG).
Al-Sada said Qatar was undaunted by other players in the market.
"We are not worried about the cycles of ups and downs in the LNG industry," he said.
"We have a huge amount of gas coming to the market but... gas demand is growing more than any other fossil fuel and it will continue growing."
Trade between Qatar and the United States is set to increase after Doha said it wanted to invest $35bn in the United States by 2020.
Qatar last year bought an almost 10% stake in the company that owns New York's iconic Empire State Building.
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