An experimental, solar-powered aircraft took off from Tulsa in the midwestern US state of Oklahoma early Saturday, kicking off the latest phase of its record-breaking quest to circle the globe without consuming a drop of fuel.
Swiss businessman Andre Borschberg, who has teamed up with adventurer Bertrand Piccard for the Solar Impulse 2 project, piloted the flight expected to last about 18 hours.
The plane, which aims to promote clean energy technologies, departed at 4:22 am fom Tulsa International Airport and was due to land at Dayton International Airport, Ohio, hours later, at 11:00 pm, project organisers said.
"The flight is part of the attempt to achieve the first ever Round-The-World Solar Flight, the goal of which is to demonstrate how modern clean technologies can achieve the impossible," they said in a statement.
"Watching Si2 silently lift off is beautiful. Science fiction in reality!" a logbook comment said on the project's website.
The journey kicked off in Abu Dhabi on March 9, 2015.
Thanks to an inflatable mobile hangar, which can be packed up quickly and transported, Solar Impulse 2 can be sheltered at a variety of locations.
The aircraft was grounded in July when its batteries were damaged halfway through its 21,700-mile (35,000-kilometre) circumnavigation of the globe.
The crew took several months to repair the damage caused by high tropical temperatures during a 4,000-mile flight between Nagoya, Japan and Hawaii.
The plane was flown on that stage by Borschberg, whose 118-hour journey smashed the previous record of 76 hours and 45 minutes set by US adventurer Steve Fossett in 2006.
He took catnaps of just 20 minutes at a time to maintain control of the pioneering plane during the flight from Japan, in what his team described as "difficult" conditions.
The Solar Impulse 2, which weighs roughly the same as a family car but has wings wider than those of a Boeing 747, contains 17,000 solar cells that power the aircraft's propellers and charge batteries.
At night, the plane runs on stored energy.
The typical flight speed is around 30 miles an hour, which can increase to double that when exposed to full sunlight.