Steven Spielberg's latest blockbuster topped the domestic box office over the four-day holiday weekend.

Warner Bros.' "Ready Player One" debuted in line with recent projections of $53 million from 4,324 locations. The virtual reality fantasy, which currently holds an A- CinemaScore and 76 percent on Rotten Tomatoes, released internationally with $128 million, bringing its worldwide total up to a solid $181.2 million.

The film based on Ernest Cline's novel stars Tye Sheridan, Olivia Cooke, Ben Mendelsohn, Mark Rylance, Simon Pegg and T.J. Miller. "Ready Player One" opened Thursday, getting a head start over its fellow weekend releases, "Tyler Perry's Acrimony" and "God's Not Dead: A Light in Darkness."

"Tyler Perry's Acrimony" -- Tyler Perry's 19th collaboration with Lionsgate -- secured second place with $17 million in 2,006 locations. Meanwhile, the third installment of the "God's Not Dead" franchise premiered with $2.6 million in 1,693 locations.

Marvel's "Black Panther" remains a powerhouse in the No. 3 slot, taking in $11 million in 2,988 locations. The blockbuster crossed the $650 million mark at the North American box office, making it the fifth-highest release in the U.S. of all time. It looks to shortly become the fourth-highest release after it passes "Jurassic World," which made $652 million. Currently, "Titanic" is at No. 3 with $659 million.

Over the Easter weekend, the faith-based "I Can Only Imagine" stayed strong in fourth place with $10.5 million in 2,648 locations, totaling $55.3 million in its three weeks of release. Rounding out the top five is Universal's "Pacific Rim" with $9.2 million in 3,708 locations. The sci-fi actioner, which held the top spot last weekend, has taken in $45.6 million domestically.

While continuing in limited release, Wes Anderson's "Isle of Dogs" made $2.9 million for a per screen average of $17,420 after expanding to 165 locations.

In total, the box office is down 21.2 percent compared to the same weekend last year, while the 2018 North American box office is down 3.8 percent from 2017.

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