Three civilians were killed and nine wounded when a mortar shell hit a crowded market in southwestern Yemen, Doctors Without Borders (MSF) said Wednesday.
Doctors Without Borders said Monday it had "temporarily frozen" operations in a rebel-held area of northwestern Yemen following an air raid on a cholera treatment centre it supports.
The figure is the highest estimated death toll yet of violence that erupted on August 25 and triggered a massive refugee crisis, with more than 620,000 Rohingya fleeing Myanmar for Bangladesh over a three-month period.
A migrant rescue ship in the Mediterranean carried hundreds of children and unaccompanied minors from over 15 countries to safety in Italy on Friday.
Doctors Without Borders (MSF) said on Saturday it was suspending its migrant rescues in the Mediterranean because it felt threatened by the Libyan coastguard and the Italian government's policies have made its job harder.
Amnesty International said Monday a US-made bomb was used in an air strike on a hospital in Yemen, urging Washington and London to stop supplying the Saudi-led coalition with weapons.
The Saudi-led coalition bombing rebels in Yemen launched an investigation on Tuesday following international condemnation of an air strike that Doctors Without Borders said killed 11 people at a hospital it supports.
Survivors of a US air strike on a hospital in Afghanistan have called for those responsible to go on trial and dismissed an American military investigation that said the bombardment did not amount to a war crime.
At least 16 more people have died of starvation in the besieged Syrian town of Madaya since an aid convoy entered earlier this month, according to Doctors Without Borders (MSF).